Dr. Linda Larson-Prior, Ph.D.

larson-priorDr. Linda Larson-Prior, Ph.D., is a Professor of Psychiatry, Neurology, Neurobiology and Developmental Sciences, and Biomedical informatics at the University of Arkansas for Medical Sciences, where I direct the Neurocognitive Dynamics Laboratory.  She is also a faculty member of the Arkansas Children’s Nutrition Center, where I direct the Brain Function Laboratory.

The research focus of her laboratories addresses the impact of environmental factors such as sleep, physical health, weight status, and mental health on cognitive function across the lifespan.  To better understand the impact of these factors on cognitive function, her laboratory employs neuroimaging, behavioral and neuropsychological methods.  To accomplish my research goals, she relies on a multi-disciplinary team of expert colleagues. Current research projects in my laboratories include:

  • Impact of childhood obesity on cognitive function in adolescents
  • Brain network organization underlying cognitive-motor dysfunction in Parkinson’s Disease
  • Dynamic organization of brain network functions that accompany cognitive deficits in aging and neurological disease
  • The impact of poor sleep quality and duration in substance use disorders
  • The impact of sleep on cognitive function across the lifespan

Publications

Altorre-Cruz, G.C., Downs, H., Hagood, D., Gu, Y., Larson-Prior, L.J. (2020) Effect of obesity on inhibitory control in preadolescents during a stop-signal task: an event-related potential study. Int. J. Psychophysiology, in review

Walden, A., Kemp, A., Larson-Prior, L., Kim, T., Gan, J., McCoy, H., Payakachat, N., Ward, W., Eswaran, H. (2020) Establishing a digital health platform in an academic medical center supporting rural communities. J Clinical Trans Sci, 1-5, doi:10.1017.cts,2020.11

Virmani, T, Gupta, H, Shah, J and Larson-Prior, L (2018) Objective measures of gait and balance in healthy non-falling adults as a function of age. Gait & Posture, 65:100-105. PMID: 30558914

Hodge, M., Horton, W., Brown, T., Herrick, R., Olsen, T., Hileman, M.E., McKay, M., Archie, K.A., Cler, E., Harms, M.P., Burgess, G.C., Glasser, M.F., Elam, J.S, Curtiss, S.W., Barch, D.M., Oostenveld, R., Larson-Prior, L.J., Ugerbil, K., Van Essen, D.E., Marcus, D.S (2015)  ConnectomeDB – Sharing human brain connectivity data.  Neuroimage, 124(PtB):1102-1107.  PMID 25934470

Larson-Prior, L.J., Oostenveld, R., Della Penna, S., Michalareas, G., Prior, F., Babajani-Feremi, A., Schofffelen, J.M., Marzetti, L., de Pasquale, F., Di Pompeo, F., Stout, J., Woolrich, M., Luo, Q., Bucholz, R., Fries, P., Pizzella, V., Romani, G.L., Corbetta, M., Snyder, A.Z. (2013) Adding dynamics to the Human Connectome Project with MEG. Neuroimage. 80:190-201 PMID 23702419

Shannon, B., Dosenbach, R., Su, Y., Vlassenko, A., Larson-Prior, L.J., Nolan, T., Snyder, A., Raichle, M.E. (2012) Morning-evening variation in human brain metabolism and memory circuits. J. Neurophysiol., 109:1444-1456. PMID 23197455

Larson-Prior, L.J., Power, J.D., Vincent, J.L., Nolan, T.S., Coalson, R.S., Zempel, J., Snyder, A.Z., Schlaggar, B.L., Raichle, M.E., Petersen, S.E. (2011) Modulation of the brain’s functional network architecture in the transition from wake to sleep. Prog. Br. Res., 193:277-294.  PMID 21854969.

Larson-Prior, L.J., Zempel, J., Nolan, T.S., Prior, F.W., Snyder, A.Z. and Raichle, M.E. (2009)  Cortical network functional connectivity is maintained in the descent to sleep. PNAS, 106:4489-4494.  PMID: PMC2657465