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Psychiatric Research Institute

Prasad R. Padala, M.D., M.S., FACHE

Prasad R. Padala
(Image credit: Johnpaul Jones)

Position

Associate Director for Clinical Programs, Geriatric Research Education and Clinical Center (GRECC), Central Arkansas Veterans Healthcare System (CAVHS)
Director, Memory Disorders Consultation Clinic, CAVHS
Director, Trancranial Magnetic Stimulation program
Professor, Department of Psychiatry, College of Medicine, University of Arkansas for Medical Sciences
Professor, Donald W. Reynolds Department of Geriatrics, College of Medicine, University of Arkansas for Medical Sciences

Contacts

Phone: 501-257-2537
UAMS email: ppadala@uams.edu
VA email: prasad.padala@va.gov

Research Expertise

Dr. Padala is a Geriatric Psychiatrist who obtained his training at the Creighton-Nebraska psychiatry program. Dr. Padala’s research interest is in the treatment of behavioral problems associated with dementia particularly apathy. He is also interested in studying the impact of apathy on outcomes of diabetes and the role of motivation in adherence to activity promotion. He is currently conducting pharmacological and non-pharmacological clinical trials for treatment of apathy. He leads the Transcranial Magnetic Stimulation lab at the GRECC, a Center of Excellence in the VA to promote geriatric knowledge through research, education and innovative clinical models.

As the Associate Director for Clinical programs for GRECC, Dr. Padala oversees seven innovative Clinical Demonstration Projects (CDPs) which utilize Quality Improvement/ Implementation Research methodology to bridge the gap between evidence based medicine and clinical practice. These CDPs are funded through grants from the Office of Rural Health, Office of Health Equity and T21 grants from the Department of Veterans Affairs.

Recent Publications

Current Publications (2009-2016)

  1. Pal S, Padala PR. Excessive yawning associated with SSRI use. Prim Care Companion J Clin Psychiatry. 2009;11(3):125-6. PMID: 19617949
  2. Burke WJ, Padala PR, Murman DL. Amyloid-Based Therapies for Alzheimer Disease: From Vaccines to Secretase Inhibitors. Primary Psychiatry 2009; 16(6): 48-52.
  3. Padala KP, Padala PR, Wengel SP. Dose dependent bradycardia with citalopram in an elderly patient. Prim Care Companion J Clin Psychiatry. 2010;12(1):PCC.09100789. doi: 10.4088/PCC.09100789blu. PMID: 20582300
  4. Bestha PD, Padala PR. A case of Catatonia Secondary to Polysubstance Abuse and Acetaminophen Overdose. Prim Care Companion J Clin Psychiatry. 2010;12(1): PCC.09100790. doi: 10.4088/PCC.09100790ecr. PMID: 20582301
  5. Padala PR, Burke WJ, Shostrom VK, Bhatia SC, Wengel SP, Potter JF, Petty F. Methylphenidate for apathy and functional status in dementia of the Alzheimer type. Am J Geriatr Psychiatry. 2010 Apr;18(4):371-4. doi: 10.1097/JGP.0b013e3181cabcf6. PMID: 20220576
  6. Padala KP, Padala PR, Potter JF. Statins: A Case For Drug Withdrawal In Patients With Dementia. J Am Geriatr Soc. 2010 Jun;58(6):1214-6. doi: 10.1111/j.1532-5415. 2010. 02889.x. PMID: 20722868
  7. Padala KP, Padala PR, Malloy T, Burke WJ. New onset multimodal hallucinations associated with mirtazapine: A case report. Int Psychogeriatr. 2010 May 26:1-3. doi: 10.1017/S1041610210000554. Epub 2010 May 26. PMID: 20500925
  8. Singh H, Selvaraj V, Padala PR. Dementia Secondary to Hyperparathyroidism. Psychiatry (Edgmont). 2010 Aug;7(8):13-4. PMID: 20877527
  9. Padala KP, Padala PR, Burke WJ. Wii-fit as an adjunct for mild cognitive impairment: clinical perspectives. J Am Geriatr Soc. 2011 May;59(5):932-3. doi: 10.1111/j.1532-5415.2011.03395.x. PMID: 21568963
  10. Franzen J, Padala PR, Wetzel M, Burke WJ. Psychostimulants for older adults. Current Psychiatry. 2012 Vol 11(1):23-32.
  11. Desouza CV, Padala PR, Haynatzki G, Anzures P, Demasi C, Shivaswamy V. Role of apathy in the effectiveness of weight management programmes. Diabetes Obes Metab. 2012 May;14(5):419-23. doi: 10.1111/j.1463-1326.2011.01544.x. Epub 2011 Dec 28. PMID: 22145671
  12. Padala PR, Padala KP, Monga V, Ramirez DA, Sullivan DH. Reversal of SSRI-Associated Apathy Syndrome by Discontinuation of Therapy. Ann Pharmacother. 2012 Mar;46 (3):e8. doi: 10.1345/aph.1Q656. Epub 2012 Feb 21. PMID: 22353235
  13. Padala PR, Desouza CV, Padala KP, Potter J, Sullivan DH, Burke WJ. Improvement of Glycemic Control With Methylphenidate Treatment of Apathy: A Preliminary Report. J Am Geriatr Soc. 2012 July;60(7):1383-4. doi: 10.1111/j.1532-5415.2012.04010.x. PMID: 22788404
  14. Padala KP, Padala PR, Malloy TR, Geske JA, Dubbert PM, Dennis RA, Garner KK, Bopp MM, Burke WJ, Sullivan DH. Wii-Fit for Improving Gait and Balance in an Assisted Living Facility: A Pilot Study. Journal of Aging Research, vol. 2012, Article ID 597573, 6 pages, 2012. doi: 10.1155/2012 / 597573. Epub 2012 Jun 13. PMID: 22745909
  15. Mikuls TR, Padala PR, Sayles HR, Yu F, Michaud K, Caplan L, Kerr GS, Reimold A, Cannon GW, Richards JS, Lazaro D, Thiele GM, Boscarino JA. Prospective study of posttraumatic stress disorder and disease activity outcomes in US veterans with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2013 Feb;65(2):227-34. doi: 10.1002/acr.21778. PMID: 22740431.
  16. Lyketsos CG, Miller DS; Neuropsychiatric Syndromes Professional Interest Area of the International Society to Advance Alzheimer’s Research and Treatment. Addressing the Alzheimer’s disease crisis through better understanding, treatment, and eventual prevention of associated neuropsychiatric syndromes. Alzheimers Dement. 2012 Jan;8(1):60-4. doi: 10.1016/j.jalz.2011.11.001. PMID: 22265590.
  17. Padala KP, Padala PR, McNeilly DP, Geske JA, Sullivan DH, Potter JF. The Effect of HMG –CoA Reductase Inhibitors on Cognition in Patients with Alzheimer’s Dementia: A Prospective Withdrawal and Rechallenge Study. Am J Geriatr Pharmacother. 2012 Oct;10(5):296-302. doi: 10.1016/j.amjopharm.2012.08.002. Epub 2012 Aug 22. PMID:22921881
  18. Dennis RA, Johnson LE, Roberson PK, Heif M, Bopp MM, Garner KK, Padala KP, Padala PR, Dubbert PM, Sullivan DH. Changes in Activities of Daily Living, Nutrient Intake, and Systemic Inflammation in Elderly Recuperative Care Patients. J Am Geriatr Soc. 2012 Nov 23. doi: 10.1111/jgs.12007. Epub 2012 Nov 23. PMID: 23176675
  19. Sullivan DH, Johnson LE, Dennis RA, Roberson PK, Garner KK, Padala PR, Padala KP, Bopp MM. Nutrient Intake, Peripheral Edema, and Weight Change in Elderly Recuperative Care Patients. J Gerontol A Biol Sci Med Sci. 2012 Nov 26. doi: 10.1093/gerona/gls234. Epub 2012 Nov 26. PMID: 23183900
  20. Neuropsychiatric symptoms in Alzheimer’s disease: past progress and anticipation of the future. Geda YE, Schneider LS, Gitlin LN, ..Padala PR et al. Neuropsychiatric Syndromes Professional Interest Area of ISTAART. Alzheimers Dement. 2013 Sep;9(5):602-8. doi: 10.1016/j.jalz.2012.12.001. Epub 2013 Apr 3. Review. PMID: 23562430
  21. Padala PR, Nabholz L, Padala KP, Ghormley C, Sullivan DH. Clock Drawing Test Over Televideo To Reach Rural Veterans: Feasibility in Community Based Outpatient Clinic in the Department of Veterans Affairs. J Am Geriatr Soc. 2015 Jan;63(1):205-6. PMID: 25597588
  22. Dennis RA, Ponnappan U, Kodell RL, Garner KK, Parkes CM, Bopp MM, Padala KP, Peterson CA, Padala PR, Sullivan DH. Immune function and muscle adaptations to resistance exercise in older adults: study protocol for a randomized controlled trial of a nutritional supplement. Trials. 2015 Mar 27;16(1):121. doi: 10.1186/s13063-015-0631-3. PMID: 25872570
  23. Garner K, Padala PR, Cox-Sullivan S. Reducing Antipsychotics for Dementia Patients in Nursing Homes. J Ark Med Soc. 2015 Jul;112(1):12-3. PMID: 26164880
  24. Monga V, Padala PR. Aripiprazole for Treatment of Apathy. Innov Clin Neurosci. 2015 Sep-Oct;12(9-10):33-36. PubMed PMID: 26634180.
  25. Padala PR, Padala KP, Garner KK, Dennis RA, Bopp MM, Sullivan DH, Burke WJ. Selective Serotonin Reuptake Inhibitors-Associated Apathy Syndrome: A Cross Sectional Study. (In Press) The Journal of Pharmacy Technology.