Professor with tenure, Department of Psychiatry and Behavioral Sciences, College of Medicine, University of Arkansas for Medical Sciences
Associate Professor, Division of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences
Associate Professor, Department of Epidemiology, College of Public Health, University of Arkansas for Medical Sciences
Staff Physician, Central Arkansas Veterans Healthcare System
Interim Associate Research Director and Site Leader for Community Engagement, South Central (VISN 16) Mental Illness Research, Education, and Clinical Center (MIRECC)
Research Health Scientist and Core Investigator, Center for Mental Healthcare and Outcomes Research (CeMHOR)
Dr. Pyne is trained as an adult psychiatrist and completed a NIMH Psychopharmacology Fellowship. Dr. Pyne has conducted cost-effectiveness analyses across a variety of mental health conditions and treatments; developed and tested collaborative care telemedicine interventions, psychophysiologic reactivity assessments, medication adherence interventions, and clergy/clinician collaboration.
Current Research Interests: cost-effectiveness analysis, telemedicine-based collaborative care, psychophysiologic assessment, and clergy/clinician collaboration.
Fortney JC, Pyne JM, Burgess JF. Population level cost effectiveness of implementing evidence based practices into routine care. Health Services Research. (to be published in the “Best of AcademyHealth” special section) In Press.
Nanney JT, Constans JI, Kimbrell TA, Kramer TL, Pyne JM. Differentiating between appraisal process and product in cognitive theories of posttraumatic stress. Psychological Trauma: Theory, Research, Practice, and Policy. In Press.
Kuhlthau K, Payakachat N, Delahaye J, Hurson J, Pyne JM, Kovacs E, Tilford JM. Quality of life for parents of children with autism spectrum disorders. Research in Autism Spectrum Disorders. In Press.
Pyne JM, Fortney JC, Mouden SB, Lu L, Hudson TJ, Mittal D. Cost Effectiveness of On-site versus Off-site Depression Collaborative Care in Rural Federally Qualified Health Centers. Psychiatric Services. In Press.
Fortney JC, Pyne JM, Kimbrell TA, Hudson TJ, Robinson DE, Schneider R, Moore WM, Custer PJ, Grubs KM, Schnurr PP. Pragmatic randomized trial of telemedicine-based collaborative care for posttraumatic stress disorder. JAMA Psychiatry. In Press.
Payakachat N, Bellando BJ, Kovacs E, Brouwer W, Kuhlthau K, Pyne JM, Tilford JM. Predicting health utilities for children with autism spectrum disorders. Autism Research. In Press.
Pyne JM, Fischer EP, Gilmore L, McSweeney J, Stewart KE, Mittal D, Bost JE, Valenstein M. (2013) Development of a Patient-Centered Antipsychotic Medication Adherence Intervention. Health Education & Behavior. Dec 25 (Epub ahead of print) PubMed PMID: 24369177
Constans JI, Kimbrell TA, Nanney JT, Marx BP, Jegley S, Pyne JM. (2014) Over-reporting bias and the modified Stroop effect in OEF/OIF Veterans with and without PTSD. Journal of Abnormal Psychology. Feb; 123(1):81-90. Nov 25 (Epub ahead of print) PubMed PMID: 24274375
Sullivan G, Hunt J, Haynes TF, Bryant K, Cheney AM, Pyne JM, Reaves C, Sullivan S, Lewis C, Barnes B, Barnes M, Hudson C, Jegley S, Larkin B, Russell S, White P, Gilmore L, Claypoole S, Smith J, Richison R. (2014). Partnering with rural faith communities to promote mental health: A multi-site program for veterans. Progress in Community Health Partnerships: Research, Education, and Action. Spring;8(1):11-9. PubMed PMID: 24859098.
Fortney JC, Enderle MA, Clothier, JL, Otero JM, Williams JS, Pyne JM. (2013) Population level effectiveness of implementing collaborative care management for depression. General Hospital Psychiatry. Sep-Oct; 35(5): 455-60. Epub 2013 May 30. PubMed PMID: 23725825
Davis-Lee EA, Carter MA,Bissett JK, Cowan PA, Pyne JM, Speck PM, Theus SA, Tolley EA. Preliminary findings of the relationship of lower heart rate variability with military sexual trauma and presumed posttraumatic stress disorder. Journal of Traumatic Stress. 2013 Apr; 26(2):249-56. PubMed PMID: 23568414
Fortney JC, Pyne JM, Mouden SB, Mittal D, Hudson TJ, Schroeder GW, Williams DK, Bynum CA, Mattox R, Rost KM. Practice based versus telemedicine based collaborative care for depression in rural Federally Qualified Health Centers: A pragmatic randomized comparative effectiveness trial. American Journal of Psychiatry. 2013 Feb 22. (Epub ahead of print). PubMed PMID: 23429924. Fortney JC, Pyne JM, Simon GE, Ludman EJ. Response to White. American Journal of Psychiatry. 2013 Aug 1;170(8):926-7. PubMed PMID: 23903337.
Kramer TL, Savary PE, Pyne JM, Kimbrell TA, Jegley SM. (2013) Veterans’ perceptions of virtual reality to assess and treat Post-Traumatic Stress Disorder. Cyberpsychology, Behavior and Social Networking. Apr;16(4):293-301. PubMed PMID: 23574368
Tilford JM, Payakachat N, Kovacs E, Pyne JM, Brouwer W, Nick T, Bellando J, Kuhlthau K. (2012) Preference-based health-related quality of life outcomes in children with autism spectrum disorders: A comparison of generic instruments. Pharmacoeconomics. Aug 1;30(8):661-79. PubMed PMID: 22788258.
Bottonari KA, Tripathi SP, Fortney JC, Curran G, Rimland D, Rodriguez-Barradas M, Gifford AL, Pyne JM. (2012) Correlates of antiretroviral and antidepressant adherence among depressed HIV-infected patients. AIDS Patient Care and STDS. May 26(5):265-73. PubMed PMID: 22536930.
Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. (2012) Effectiveness-implementation hybrid designs: Combining elements of clinical effectiveness and implementation research to enhance public health impact. Medical Care. Mar 50(3):217-26. PubMed PMID: 22310560
McLay RN, Grapp K, Spira JL, Perlman K, Johnston SL, Rothbaum BO, Difede J, Deal W, Schilling R, Oliver D, Baird A, Bordnick PS, Spitalnick J, Pyne JM, Rizzo A. (2012) Development and testing of virtual reality exposure therapy for post traumatic stress disorder in active duty service members who served in Iraq and Afghanistan. Military Medicine. Jun 177(6):635-42. PubMed PMID: 22730837
Kimbrell T, Pyne JM, Kunik ME, Magruder KM, Petersen NJ, Yu HJ, Hudson TJ, Schulz PE, Qureshi SU. (2011) The impact of Purple Heart commendation and PTSD on mortality rates in older veterans. Depression and Anxiety. Dec 21;28(12):1086-90. (July 12 Epub ahead of print) PubMed PMID: 21751302.
Curran GM, Pyne J, Fortney JC, Gifford A, Asch SM, Rimland D, Rodriguez-Barradas M, Munson TP, Kilbourne AM, Hagedorn H, Atkinson JH. (2011) Development and implementation of collaborative care for depression in HIV clinics. AIDS Care. Dec 23(12):1626-36. (June 30 Epub ahead of print) PubMed PMID: 21714689.
Deen TL, Fortney JC, Pyne JM. (2011) Relationship between satisfaction, patient-centered care, adherence, and outcomes among patients in a collaborative care trial for depression. Administration and Policy in Mental Health and Mental Health Services Research. Sep; 38(5): 345-55. PubMed PMID: 20978932.
Fortney JC, Pyne JM, Edlund MJ, Stecker T, Mittal D, Robinson DE, Henderson KL. (2011) Reasons for antidepressant non-adherence among veterans treated in primary care clinics. Journal of Clinical Psychiatry. Jun; 72(6): 827-34. Epub 2010 Nov 16. PubMed PMID: 21208579.
Fortney JC, Maciejewski ML, Tripathi, SP, Deen TL, Pyne JM. (2011) A budget impact analysis of telemedicine-based collaborative care for depression. Medical Care. Sep;49(9):872-880. PubMed PMID: 21623240
Wood DP, Webb-Murphy J, McLay RN, Wiederhold BK, Spira JL, Johnston S, Koffman RL, Wiederhold MD, Pyne J. (2011) Reality graded exposure therapy with physiological monitoring for the treatment of combat related post traumatic stress disorder: a pilot study. Studies in Health Technology and Informatics. 163:696-702. PubMed PMID: 21335883.
McLay RN, Wood DP, Webb-Murphy JA, Spira JL, Wiederhold MD, Pyne JM, Wiederhold BK. (2011) A randomized, controlled trial of virtual reality-graded exposure therapy for post-traumatic stress disorder in active duty service members with combat-related post-traumatic stress disorder. Cyberpsychology, Behavior and Social Networking. Apr;14(4):223-229. PubMed PMID: 21332375.
Pyne JM, Tripathi S, French M, McCollister K, Rapp RC, Booth BM. (2011) Longitudinal association of preference-weighted health-related quality of life measures and substance use disorder outcomes. Addiction. 106(3):507-15. PubMed PMID: 21205046.
Qureshi S, Long ME, Bradshaw MR, Pyne JM, Magruder KM, Kimbrell T, Hudson TJ, Jawaid A, Schulz PE, Kunik ME. (2011) Does PTSD impair cognition beyond the effect of trauma? The Journal of Neuropsychiatry and Clinical Neurosciences. 23(1):16-28. PubMed PMID: 21304135.
Pyne JM, Fortney JC, Curran GM, Tripathi S, Atkinson JH, Kilbourne AM, Hagedorn HJ, Rimland D, Rodriguez-Barradas MC, Monson T, Bottonari KA, Asch SM, Gifford AL. (2011) Effectiveness of collaborative care for depression in human immunodeficiency virus clinics. Archives of Internal Medicine. 171(1):23-31.
Mittal D, Fortney JC, Pyne JM, Wetherell JL. (2010) Predictors of persistence of co-morbid generalized anxiety disorder among veterans with major depression. Journal of Clinical Psychiatry. Dec 14. (Epub ahead of print) PubMed PMID: 21208594.
Fortney JC, Pyne JM, Edlund MJ, Mittal D. (2010) Relationship between antidepressant medication possession and treatment response. General Hospital Psychiatry. Jul-Aug; 32(4): 377-9. Epub 2012 May 4. PubMed PMID: 20633741.
Pyne JM. Commentary on Dietze et al: Moving patient-centered health outcomes forward. (2010) Addiction. 105(12):2149-50. PubMed PMID: 21108510.
Fortney, JC, Pyne JM, Steven CA, Williams JS, Hedrick RG, Lunsford AK, Raney WN, Ackerman BA, Bonner, LM, Smith JL. (2010) A web-based clinical decision support system for depression care management. American Journal of Managed Care. 16(11):849-854. PubMed PMID: 21348556.
Kramer T, Pyne J, Kimbrell T, Savary P, Smith J, Jegley S. (2010) Clinician perceptions of virtual reality to assess and treat returning veterans. Psychiatric Services. 61(11):1153-1156. PubMed PMID: 21041358.
Qureshi SU, Kimbrell T, Pyne JM, Magruder KM, Hudson TJ, Petersen NJ, Yu HJ, Schulz PE, Kunik ME. (2010) Greater prevalence and incidence of dementia in older veterans with PTSD. Journal of the American Geriatrics Society. 58:1627-1633. PubMed PMID: 20863321.
Pyne JM, Fortney JC, Tripathi S, Maciejewski ML, Edlund MJ, Williams DK. (2010) Cost effectiveness analysis of a rural telemedicine collaborative care intervention for depression. Archives of General Psychiatry. 67:812-821. Abstract was re-printed in Journal of the American Medical Association. (2010) 304(13):1425. PubMed PMID: 20679589.
Wood DP, Murphy J, Center K, McLay R, Koffman R, Johnston S, Spira J, Pyne JM, Wiederhold B. (2009) Combat related post traumatic stress disorder: A case report using virtual reality graded exposure therapy with physiological monitoring with a female seabee. Military Medicine. 174(11):1215-22. PubMed PMID: 19960832.
Wood DP, Murphy J, McLay R, Koffman R, Spira J, Obrecht RE, Pyne J, Wiederhold BK. (2009) Cost effectiveness of virtual reality graded exposure therapy with physiological monitoring for the treatment of combat related post traumatic stress disorder. Studies in Health Technology and Informatics. 144:223-9. PubMed PMID: 19592768.
McCollister KE, French MT, Pyne JM, Booth B, Rapp R, Carr C. (2009) The cost of treating addiction from the client’s perspective: Results from a multi-modality application of the Client DATCAP. Drug and Alcohol Dependence. 104(3): 241-248. PubMed PMID: 19574000.
Qureshi S, Pyne JM, Magruder K, Schulz PE, Kunik ME. (2009) The link between post-traumatic stress disorder and physical comorbidities: A systematic review. Psychiatric Quarterly. 80(2): 87-97. PubMed PMID: 19291401.
Pyne JM, Fortney J, Tripathi S, Feeny D, Ubel P, Brazier J. (2009) How bad is depression? Preference score estimates from depressed patients and the general population. Health Services Research. 44(4): 1406-23. PubMed PMID: 19453391.
Fortney J, Pyne JM, Smith J, Curran G, Otero J, Enderle M, McDougall S. (2009) Steps for Implementing Collaborative Care Programs for Depression. Population Health Management. 12(2): 69-79. PubMed PMID: 19320606.
Ackerman B, Pyne JM, Fortney J. (2009) Challenges associated with being an off-site depression care manager. Journal of Psychosocial Nursing and Mental Health, 47(4) 43-49. PubMed PMID: 19437931.
Liu CF, Rubenstein LV, Kirchner JE, Fortney JC, Perkins MW, Ober SK, Pyne JM, Chaney EF. (2009) The organizational cost of quality improvement for depression care. Health Services Research, 44(1):225-44. PubMed PMID: 19146566.
Pyne J, Asch S, Lincourt K, Kilbourne A, Bowman C, Atkinson H, Gifford A. (2008) Quality indicators for depression care in HIV patients. AIDS Care, 20(9):1075-1083. PubMed PMID: 18825515.
Canuso A, McLay RN, Bennett JH, Pyne JM, Munoz KB, Stenback KA. (2008) Schizophreniform disorder after heat injury in a military recruit. Psychosomatics, 49(4):345-346. PubMed PMID: 18621941.
Fischer EP, McSweeney JC, Pyne JM, Naylor J, Williams DK, Blow F, Owen RR. (2008) Family involvement modifies the effect of substance use on sustained utilization of services for schizophrenia. Psychiatric Services, 59(8):902-908. PubMed PMID: 18678688.
Pyne JM, French M, McCollister K, Tripathi S, Rapp R, Booth B. (2008) Preference-weighted health-related quality of life measures and substance use disorder severity. Addiction, 103:1320-1329. Preference-weighted health-related quality of life and addiction – a reply. Addiction, 103:1331-1332. PubMed PMID: 18397359.
Pyne JM, Labbate C. (2008) Ranking of outcome domains for use in real-time outcomes feedback laboratory by patients with schizophrenia. Journal of Nervous and Mental Disease, 196(4):336-339. PubMed PMID: 18414130.
Wood DP, Murphy JA, Center KB, Russ C, McLay R, Reeves D, Pyne J, Shilling R, Wiederhold, BK. (2008) Combat related post-traumatic stress disorder: a multiple case report using virtual reality graded exposure therapy with physiological monitoring. Studies in Health Technology and Informatics, 132:556-561.
Edlund ME, Fortney J, Reeves-Powell C, Pyne JM, Mittal D. (2008) Beliefs about depression and depression treatment among depressed veterans. Medical Care, 46(6):581-589.
Liu CF, Fortney J, Vivell S, Vollen K, Raney W, Revay B, Barcia-Maldonado, Pyne J, Rubenstein L, Chaney E. (2007) Time allocation and caseload capacity in telephone depression care management. American Journal of Managed Care, 13:652-660.
Fortney JC, Pyne JM, Edlund MJ, Williams DK, Robinson DE, Mittal D, Henderson KL. A randomized trial of telemedicine-based collaborative care for depression. (2007) Journal of General Internal Medicine, 22(8):1086-1093.
Wood DP, Murphy J, Center K, McLay R, Reeves D, Pyne JM, Shilling R, Wiederhold, BK. (2007) Combat-related post-traumatic stress disorder: A case report using virtual reality exposure therapy with physiological monitoring. Cyberpsychology & Behavior, 10(2):309-315.
Pyne JM, Tripathi S, Williams DK, Fortney J. Depression free day to utility weighted score: is it valid? (2007) Medical Care, 45(4):357-362.
Mittal D, Fortney J, Pyne JM, Edlund M, Wetherell J. (2006) Impact of comorbid anxiety disorders on health-related quality of life among patients with major depressive disorder. Psychiatric Services, 57 (12):1731-37.
Mancino MJ, Pyne JM, Tripathi S, Constans J, Roca V, Freeman T. (2006) Generic health-related quality of life in a veteran population with post-traumatic stress disorder. Journal of Nervous and Mental Disease, 194(11):877-879.
Pyne JM, McSweeney J, Kane HS, Harvey S, Bragg L, Fischer E. (2006) Agreement between patients with schizophrenia and providers on factors of antipsychotic medication adherence. Psychiatric Services, 57: 1170-1178.
Mittal D, Davis EC, Depp C, Pyne JM, Golshan S, Patterson TL, Jeste DV. (2006) Correlates of health-related quality of well-being in older patients with schizophrenia. Journal of Nervous and Mental Disease, 194(5):335-40.
Spira JL, Pyne JM, Wiederhold B, Wiederhold M, Graap K, Rizzo A. (2006) Virtual reality and other experiential therapies for combat-related PTSD. Primary Psychiatry, 13(3):58-64. Reprinted in Polish post-graduate psychiatry journal as: Spira J, Pyne J, Wiederhold B, Wiederhold M, Graap K, Rizzo A. (2007) Desensytyzacja w rzeczywistosci wirtualnej i inne meody terapii wykorzystujacych doswiadczenie w leczeniu zaburzenia stresowego pourazowego, powstalego w wyniku dzialan wojennych. Psychiatria po Dyplomie, Tom 4, Nr 1:32-38.
Pyne JM, Booth BM, Farahati F, Tripathi S, Smith GR, Marques PR. (2006) Preference-weighted health status associated with substance use disorders treatment. Journal of Studies on Alcohol, 67(3):436-444.
Steffick DE, Fortney JC, Smith JL, Pyne JM. (2006) Worksite disease management programs for depression: potential employer benefits. Disease Management and Health Outcomes, 14(1):13-26.
Fortney JC, Pyne JM, Edlund MJ, Robinson DE, Mittal D, Henderson KL. (2006) Design and Implementation of the telemedicine enhanced antidepressant management study. General Hospital Psychiatry, 28(1):18-26.
Stein MB, Roy-Byrne PP, Craske MG, Engelhardt R, Bystritsky A, Sullivan G, Pyne JM, Katon W, Sherbourne CD. (2005) Functional impact and health utility of anxiety disorders in primary care outpatients. Medical Care, Dec;43(12):1164-70.
Goeree R, Farahati F, Burke N, Blackhouse G, O’Reilly D, Pyne J, Tarride JE. (2005) The economic burden of schizophrenia in Canada in 2004. Current Medical Research Opinion, 21(12):2017-28.
Pyne JM, Rost KM, Farahati F, Tripathi S, Smith J, Williams DK, Fortney J, Coyne JC. (2005) One size fits some: the impact of patient treatment attitudes on the cost-effectiveness of a depression primary care intervention. Psychological Medicine, 35:839-854.
Tilford JM, Grosse SD, Robbins JM, Pyne JM, Cleves MA, Hobbs CA. (2005) Health state preferences scores of children with spina bifida and their caregivers. Quality of Life Research, 14:1087-1098.
Rost K, Pyne JM, Elliott CE, deGruy F, Dickinson M. (2005) Cost-effectiveness of enhancing primary care depression management on an ongoing basis. Annals of Family Medicine, 3(1):7-14.
Pyne JM, Kuc EJ, Schroeder P, Fortney J, Edlund M, Sullivan G. (2004) Relationship between perceived stigma and depression. Journal of Nervous and Mental Disease, 192(4):278-283.
Hudson TJ, Owen RR, Thrush C, Han X, Pyne JM, Thapa P. (2004) A pilot study of barriers to medication adherence in schizophrenia. Journal of Clinical Psychiatry, (2):208-217.