Michael Mancino, M.D.

MancinoDr. Michael Mancino, M.D., graduated medical school from Northeastern Ohio Universities College of Medicine. He trained for several years in neurological surgery and ultimately completed his training at UAMS in psychiatry in 2004. He is board certified by the American Board of Psychiatry and Neurology as well as the American Board of Preventive Medicine in addiction medicine. He is professor at the UAMS Psychiatric Research Institute and currently the Program Director for the Center for Addiction Services and Treatment. He is also past Medical Director of the Recovery Centers of Arkansas. He focuses his clinical practice on medication for opioid use disorders (MOUD).

Dr. Mancino also has an interest in conducting clinical trials for medications development for patients with psychostimulant and opioid use disorders and is funded by the National Institute on Drug Abuse (NIDA).

“Improving Treatments for Prescription Opioid Dependence”
Principal Investigators: Michael J. Mancino, M.D. and Alison Oliveto, Ph.D.
Agency: National Institute on Drug Abuse
Type: R01 (DA036544-01A1)

“Expanding Medication Assisted Treatment Training for Prescription Opioid Use Disorders in Arkansas”
Principal Investigator: Deborah Motley-Bledsoe
Role: Site PI
Agency: Arkansas Division of Behavioral Health Services from SAMHSA STR Grant

“Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence”
Principal Investigator: Michael J. Mancino, M.D.
Agency: National Institute on Drug Abuse
Type: R21 (DA034824-02)

Click here to learn more about Dr. Mancino’s work with Medication Assisted Treatment Recovery Initiative for Arkansas Rural Communities (MATRIARC).


McGaugh, J., Mancino, M.J., Feldman, Z., Chopra, M.P., Gentry, W.B., Cargile, C., Oliveto, A.O. Open Label Pilot Study of Modafinil for Methamphetamine Dependence. The Journal of Clinical Psychopharmacology. 2009, Oct; 29(5): 488-91. PMC3610177

Mancino, M.J., Feldman, Z., McGaugh, J., and Oliveto, A. Effect of PTSD diagnosis and contingency management procedures on cocaine use in opioid-dependent cocaine abusers maintained on low- vs. high-dose LAAM. The American Journal on Addictions. 2010, Mar-Apr; 19(2): 169-177. PMC3472706

Mancino, M., Curran, G., Xiatong, H., Allee, E., Humphreys, K., Booth, B. Predictors of Attrition from a National Sample of Methadone Maintenance Patients. The American Journal of Drug and Alcohol Abuse. 2010, May; 36(3): 155-160. PMC3314423

Bickel, W.K., Jones, B.A., Landes, R.D., Christensen, D.R., Jackson, L., Mancino, M. Hypothetical intertemporal choice and real economic behavior: delay discounting predicts voucher redemptions during contingency-management procedures. Experimental and Clinical Psychopharmacology. 2010 Dec; 18(6): 546-52. PMC4034533

Oliveto, A., Poling, J., Mancino, M., Feldman, Z., Cubells, J., Pruzinsky, R., Gonsai, K., Cargile, C., Sofuoglu, M., Chopra, M., Gonzalez-Haddad, G., Carroll, K., Kosten, T. Randomized, double blind, placebo-controlled trial of Disulfiram for the Treatment of Cocaine Dependence in Methadone-Stabilized Patients. Drug and Alcohol Dependence. 2011 Jan 15; 113(2-3): 184-91. PMC3005977

Mancino, M.J., Gentry, W.B., Feldman, Z., Mendelson, J.E., and Oliveto, A. Characterizing methamphetamine withdrawal in recently abstinent methamphetamine users: A pilot field study. The American Journal of Drug and Alcohol Abuse. 2011 Mar; 37(2): 131-6. PMC3063384

Oliveto, A., Poling, J., Mancino, M.J., Williams, D.K., Thostenson, J., Pruzinsky, R., Gonsai, K., Sofuoglu, M., Gonzalez, G., Tripathi, S., and Kosten, T.R. Sertraline delays relapse in recently abstinent cocaine- dependent patients with depressive symptoms. Addiction. 2012 Jan;107(1):131-41 PMC3237722

Oliveto, A; Mancino, M.J., Sanders, N., Cargile, C.S., Guise, J.B., Bickel, W.K., and Gentry, W.B. Effects of Prototypic Calcium Channel Blockers in Methadone-Maintained Humans Responding Under a Naloxone Discrimination Procedure. Eur J Pharmacol (2013), Sept; 715(1-3):424-435. PMC3759565

Atkinson, T.S., Sanders, N., Mancino, M.J., and Oliveto, A. Effects of Disulfiram on QTc Interval in non-Opioid Dependent and Methadone-Treated Cocaine Dependent Patients. Journal of Addiction Medicine. 2013 Jul-Aug; 7(4):243-8. PMC3737260

Sanders, N.C., Mancino, M.J., Gentry, W.B., Guise, J.B., Bickel, W.K., Thostenson, J., and Oliveto, A.H. Randomized, Placebo-Controlled Pilot Trial of Gabapentin During an Outpatient, Buprenorphine-Assisted Detoxification Procedure. Exp Clin Psychopharmacol. 2013 Aug; 21(4):294-302. PMC3972066

Oliveto, A.H., Mancino, M.J.,, Ingerman, S., Day, S., and Kramer, T. Acceptability of shamanic healing for treating psychostimulant dependence: a pilot survey. Focus on Alternative and Complementary Therapies. 2014, March; 19(1): 16–21.

Kaley, S., Mancino, M.J., and Messias, E. Sadness, Suicide, and Drug Misuse in Arkansas: Results from the Youth Risk Behavior Survey 2011. The Journal of the Arkansas Medical Society. 2014 Feb; 110(9):185-186.

Mancino, M.J., McGaugh, J., Chopra, M.P., Guise, J.B., Christopher Cargile, C., Williams, D.K., Thostenson, J, Kosten, T.R., Sanders N., and Oliveto, A. Clinical Efficacy of Sertraline Alone and Augmented with Gabapentin in Recently Abstinent Cocaine-Dependent Patients with Depressive Symptoms. J Clin Psychopharmacol. 2014 Apr; 34(2):234-9. PMC4068618

Christensen, D. R., Landes, R. D., Jackson, L., Marsch, L. A., Mancino, M., Chopra, M. P., Bickel, W. K. Adding an Internet-delivered Treatment to an Efficacious Treatment Package for Opioid Dependence. J of Consulting and Clinical Psychology. J Consult Clin Psychol. 2014 Dec;82(6):964-72. PMC4244262

Kumar N, Stowe ZN, Han X, Mancino MJ. Impact of early childhood trauma on retention and phase advancement in an outpatient buprenorphine treatment program. Am J Addict. 2016 Oct; 25(7):542-8.

Bashiri M, Mancino M, Stanick V, Thostenson J, Kosten T, Oliveto A. Moderators of Response to Sertraline Versus Placebo Among Recently Abstinent, Cocaine Dependent Patients: A Retrospective Analysis of Two Clinical Trials. Am J Addict. 2017 Dec;26(8):807-814. PMC5699965

Nahata R, Mancino MJ, Thostenson J, Oliveto AH. Survey of Treatment Preferences for Opioid Use Disorder. Jacobs J Addict Ther. 2018;5 (3). Epub 2018 Nov 27. PMC6530927.

Wilson M, Cucciare M, Porter A, Chalmers C, Mullinax S, Mancino MJ, Oliveto AH. The utility of a statewide prescription drug-monitoring database vs the Current Opioid Misuse Measure for identifying drug-aberrant behaviors in emergency department patients already on opioids. Am J Emergency Medicine. 2020, March 38(3):503-507.