• Skip to main content
  • Skip to main content
Choose which site to search.
University of Arkansas for Medical Sciences Logo University of Arkansas for Medical Sciences
Psychiatric Research Institute
  • UAMS Health
  • Jobs
  • Giving
  • Clinical Care
    • Outpatient Care
      • AR ConnectNow
      • Center for Addiction Services and Treatment
        • Improving Access To Treatment For Opioid Use Disorder
        • MATRIARC
          • Project ECHO
        • Medication and Counseling Treatment
        • Medications To Treat Opioid Use Disorders
        • Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
        • Suboxone Treatment Program
        • Subutex Treatment Program
        • What is Buprenorphine?
        • What Is Methadone?
        • What Is Naltrexone?
        • What Is Vivitrol?
        • Drugs and Addiction
        • New Hybrid Care Program
        • Opioid Use Disorder
      • Child Study Center
        • Dialectical Behavior Therapy
        • Family Resources
          • Handouts for Parents
          • Books
          • Videos
        • Meet the Team – Child Study Center
        • Treatment and Services
      • Psychiatry Clinic in Fayetteville
        • Meet the Team
      • Six Bridges Clinic
      • STRIVE
      • Walker Family Clinic
        • Mental Health Resources
      • Women’s Mental Health Program
        • Peer Support Specialist Services
        • Reproductive Psychiatry Fellowship
        • Substance Use Treatment
        • WMHP Research
        • Women’s Inpatient Unit – 5 North
        • Women’s Mental Health Clinic
        • Women’s Mental Health Program – Fayetteville Branch
      • Odyssey Clinic
        • Northwest Arkansas Schizophrenia Conference 2025 Media
        • Schizophrenia Conference 2024 Media
      • Neuropsychology
    • Inpatient Units
      • Child Diagnostic Unit
        • Child Diagnostic Unit Videos
      • Women’s Inpatient Unit – 5 North
    • Interventional Psychiatry
      • Electroconvulsive Therapy
      • Esketamine
      • Ketamine Infusions
      • SAINT® Neuromodulation System
    • Crisis Stabilization Unit
      • Pulaski County Regional Crisis Stabilization Unit
        • Operation SAVE
  • News
  • PRI Journal
  • Education
  • Research
    • Center for Addiction Research
      • Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
      • What is Vivitrol?
      • Faculty
        • Alison Oliveto, Ph.D
        • Merideth Addicott, Ph.D.
        • Michael Mancino, M.D.
        • Nihit Kumar, M.D.
    • Center for Health Services Research
      • Behavioral Health QUERI
      • Health Services Research and Development Service
      • Rural Outreach Program
        • Rural Outreach Program Team
      • South Central (VISN 16) Mental Illness Research, Education and Clinical Center
      • Center for Health Services Research Faculty and Staff
        • Brandon J. Griffin, Ph.D.
        • Christopher Long, Ph.D.
        • Corey Hayes, Pharm.D., Ph.D., MPH
        • Eva Woodward, Ph.D.
        • Jacob Painter, Pharm.D, Ph.D.
        • Kent D. Hinkson, Ph.D.
        • Leah Tobey, PT, DPT, MBA
        • Marcela Weber, Ph.D.
        • Mary J. Bollinger, MPH, Ph.D.
        • Meghan Breckling, Pharm.D., BCACP
        • Melissa J. Zielinski, Ph.D.
        • Michael Cucciare, Ph.D.
        • Michael Wilson, M.D., Ph.D., FAAEM, FACEP
        • Prasad R. Padala, M.D., M.S., FACHE
        • Rajinder “Sonia” Singh, Ph.D.
        • Rebecca Raciborski, Ph.D.
        • Ronald G. Thompson, Jr., Ph.D., LCSW
        • Sara J. Landes, Ph.D.
        • Traci Abraham, Ph.D.
        • Angie Waliski, Ph.D.
        • Ellen P. Fischer, Ph.D.
        • Geoffrey M. Curran, Ph.D.
        • Greer Sullivan, M.D., M.S.P.H.
        • Jeffrey M. Pyne, M.D.
        • JoAnn Kirchner, M.D.
        • Joy Reeves Pemberton, Ph.D.
        • Karen Drummond, Ph.D.
        • Kristen M. Viverito, Psy.D.
        • Puru Thapa, M.D., M.P.H.
        • Richard R. Owen, M.D.
        • Teresa Hudson, Pharm.D., Ph.D.
        • Teresa L. Kramer, Ph.D.
      • Postdoctoral Fellowship
        • CeMHOR/HSR&D
        • MIRECC
    • Health and the Legal System (HEALS) Lab
      • Projects in the Health and the Legal System (HEALS) Lab
      • Publications and Media
      • About the HEALS Lab
    • Neurodevelopmental Risk and Resilience Program
    • Research Trials
    • Trauma REsilience & Community Collaboration (TRECC)
      • About TRECC
      • Get Involved
      • Research
        • Current Projects
        • Media
        • Selected Research Publications
      • Resources
        • Measures
        • Tools And Tool Kits
    • Helen L. Porter and James T. Dyke Brain Imaging Research Center
  • Patients and Visitors
    • Art of the Psychiatric Research Institute
    • Mental Health Resources
    • Mission And Vision Statements
    • Social Media
    • Map and Directions
    • Job Openings
    • Faculty and Staff
    • Giving
  1. University of Arkansas for Medical Sciences
  2. Psychiatric Research Institute
  3. Clinical Care at the UAMS Psychiatric Research Institute
  4. Interventional Psychiatry at the UAMS Psychiatric Research Institute
  5. SAINT® Neuromodulation System

SAINT® Neuromodulation System

The Psychiatric Research Institute (PRI) is one of the first facilities in the nation to partner with Magnus Medical, Inc., to implement the SAINT® neuromodulation system, an innovative, one-of-a-kind therapy for treatment-resistant depression. The SAINT system uses magnetic resonance imaging (MRI) to pinpoint the optimal anatomical target for precise transcranial magnetic stimulation (TMS) in individuals with major depression. The targeting process helps identify the location and correct stimulation dosing for each patient. A specialized pattern of magnetic pulses is then delivered to cause neurons to fire and rebuild connectivity.

The SAINT treatment protocol at PRI relies on the unique capabilities of the Helen L. Porter and James T. Dyke Brain Imaging Research Center’s MRI scanner. The MRI scan, which takes approximately 45 minutes, will occur prior to treatment. Using the MRI scan, the individual patient’s optimal treatment target is mapped by Magnus’ technology. SAINT treatment consists of 10 sessions per day for five consecutive days. Each session includes 10 minutes of stimulation followed by a 50-minute rest period. Treatment is non-invasive, and the most common side effect is headache.

Read an American Journal of Psychiatry article about SAINT.

Patients can potentially start experiencing symptom relief within days (versus weeks when standard TMS protocols are used). In a double-blinded randomized controlled trial (RCT) evaluating SAINT, 79 percent of people in the active treatment group experienced remission of their depression symptoms following the five-day treatment protocol, compared to people in the control group (13 percent remission rate) who received a “sham” (placebo) treatment.

Patient referrals should be faxed to 501-603-1897. Call 501-526-8650 to set up a consultation.

Psychiatric Research Institute LogoPsychiatric Research InstitutePsychiatric Research Institute
Mailing Address: 4224 Shuffield Drive, Little Rock, AR 72205
Phone: (501) 526-8100
  • Facebook
  • X
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy Statement

© 2025 University of Arkansas for Medical Sciences